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by L EchavarrÃa-Consuegra · 2021 · Cited by 1 — chronic respiratory disease are more likely to develop a serious illness. ... Targeting the unfolded protein response in coronavirus infection ... serum-free medium (Opti-MEM; Gibco-BRL) and liposomes were set up as recommended by ... Supplementary Materials and Methods. (PDF). Acknowledgments. baf94a4655 nethelgy
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Aug 10, 2009 — View PDF · View PDF Plus. Tools ... ER chaperones target unfolded or misfolded proteins that enter the ER, thereby simultaneously ... GRP78 also has been shown in a cell-free system to inhibit cytochrome ... Potential strategies aimed at reducing human diseases by blocking ER stress and UPR activation.. thought to be a benign disease with excellent prognosis. Still, our group and ... X-​box binding protein 1 (XBP1); the UPR target genes Gadd34 and EDEM; and .... Furthermore, unresolved ER stress has been implicated in a variety of metabolic disorders, such as obesity and type 2 diabetes. Therefore, intervening in ER ...
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